Inflisiran (CAS: 1639324-58-5) Series Intermediate Professional Supplier

[Dec 11, 2025]

With the technological innovation in the field of cardiovascular disease treatment, Inclisiran (CAS: 1639324-58-5), as a milestone small interfering RNA (siRNA) lipid-lowering drug, continues to rise in market demand due to its long-term and precise therapeutic advantages. To assist global pharmaceutical companies and research institutions in efficiently promoting the research and production of Inclisiran, we rely on a mature R&D and production system and strict quality control standards to professionally supply Inclisiran's fully synthetic intermediate series, providing stable and high-purity core raw material support for your project!


	2'-OMe N-Bz Adenosine Amidite	110782-31-5
	2'-OMe N-iBu Guanosine Amidite	150780-67-9
	2'-OMe N-Ac Cytidine Amidite	199593-09-4
	2'-OMe Uridine Amidite	110764-79-9
	2'-Fluoro N-Bz Adenosine Amidite	136834-22-5
	2'-Fluoro N-iBu Guanosine Amidite	144089-97-4
	2'-Fluoro N-Ac Cytidine Amidite	159414-99-0
	2'-Fluoro Uridine Amidite	146954-75-8
		98796-51-1

1. Laboratory development stage of Inclisiran drug (process route exploration, small-scale trial optimization);
2. Pilot production and industrial mass production of Inclisiran;
3. Research projects related to structural modification and process improvement of nucleic acid drugs.

We have been deeply involved in the field of nucleic acid drug intermediates for many years, accurately matching the synthesis process requirements of Inclisiran. The intermediates we supply cover key fragments and modified monomers in its entire synthesis process, including but not limited to:

-Core modified nucleoside intermediates: ribonucleosides and deoxyribonucleoside derivatives modified at different sites, which are the core basic raw materials for the construction of Inclisiran nucleotide chains;

-Connectors and Activation Intermediates: Provides specialized intermediates for nucleotide chain linkage and end modification, ensuring the high efficiency and specificity of chain extension reactions;

-Protective group modified intermediates: including various high-performance protective group reagents and modified products, meeting the precise regulation requirements of group protection and deprotection in the synthesis process of Inclisiran;

-Customized intermediates: We can provide exclusive customized synthesis services based on the process route and structural drawings provided by customers, to solve the raw material pain points in special process links.

All intermediates are optimized and designed based on the characteristics of the Inclisiran synthesis process, ensuring high compatibility with subsequent reactions and effectively improving synthesis yield and product purity.

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